Narcotic the loser in an acute migraine trial.

A clinical trial called Hydromorphone Versus Prochlorperazine + Diphenhydramine for Acute Migraine compared 2 treatment strategies for patients with severe migraine headaches, being treated in an Emergency Department setting.  The subjects were randomized to the narcotic hydromorphone (Dilaudid) 1 mg vs. prochlorperazine (Compazine) 10 mg and diphenhydramine (Benadryl) 25 mg all given intravenously.  The trial was stopped […]